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Please note that Cumberland Pharmaceuticals cannot guarantee the availability of ACETADOTE at the facilities listed on this site. Based on the most current information available to Cumberland Pharmaceuticals, these facilities have purchased ACETADOTE.

Important Safety Information

ACETADOTE is contraindicated in patients with hypersensitivity or previous anaphylactoid reactions to acetylcysteine or any components of the preparation. Serious anaphylactoid reactions, including death in a patient with asthma, have been reported in patients administered acetylcysteine intravenously.

ACETADOTE should be used with caution in patients with asthma, or where there is a history of bronchospasm. The total volume administered should be adjusted for patients less than 40 kg and for those requiring fluid restriction. To avoid fluid overload, the volume of diluent should be reduced as needed. If volume is not adjusted, fluid overload can occur, potentially resulting in hyponatremia, seizure, and death.

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